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  <xs:element id="anab_GlaxoSmithKlineMember" abstract="true" name="GlaxoSmithKlineMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="anab_NoncashAdvanceFutureRoyaltiesIssuanceCostsIncurredButNotYetPaid" abstract="false" name="NoncashAdvanceFutureRoyaltiesIssuanceCostsIncurredButNotYetPaid" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="anab_RevenueRecognitionMilestoneMethodContingentUponPreclinicalAndClinicalTrialEvents" abstract="false" name="RevenueRecognitionMilestoneMethodContingentUponPreclinicalAndClinicalTrialEvents" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="anab_ClearanceOfInvestigationalNewDrugFromFDAMember" abstract="true" name="ClearanceOfInvestigationalNewDrugFromFDAMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="anab_ProceedsFromSaleOfAdvanceFutureRoyalties" abstract="false" name="ProceedsFromSaleOfAdvanceFutureRoyalties" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="anab_CollaborationLicenseAgreementUpfrontMilestoneAndRoyaltyExpense" abstract="false" name="CollaborationLicenseAgreementUpfrontMilestoneAndRoyaltyExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="anab_LiabilitiesRelatedToSaleOfFutureRoyaltiesLineItems" abstract="true" name="LiabilitiesRelatedToSaleOfFutureRoyaltiesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
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  <xs:element id="anab_CashAndCashEquivalentsAndRestrictedCashFairValueDisclosure" abstract="false" name="CashAndCashEquivalentsAndRestrictedCashFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="anab_RevenueRecognitionMilestoneMethodContingentUponCertainUnitedStatesAndEuropeanRegulatorySubmissionsAndApprovals" abstract="false" name="RevenueRecognitionMilestoneMethodContingentUponCertainUnitedStatesAndEuropeanRegulatorySubmissionsAndApprovals" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>
